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The infection usually goes away with antifungal medication, but scarring inside the lung often remains. Many patients will still be sick due to their pre-existing lung disease.
Often times, those who have had chronic pulmonary histoplasmosis must follow up with their doctor, who will check for signs of relapse.
In rare cases, a pulmonary histoplasmosis infection can spread through the blood to other organs. This is called disseminated histoplasmosis. People who have suppressed immune systems and very young children are more likely to develop this condition. If this occurs, the prognosis is less favorable.
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