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The goals of treatment are to control the acute attacks, prevent recurrent attacks, and promote healing of the colon. Hospitalization is often required for severe attacks. Corticosteroids may be prescribed to reduce inflammation.
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Medications that may be used to decrease the frequency of attacks include 5-aminosalicylates such as mesalamine and immunomodulators such as azathioprine and 6-mercaptopurine.
Surgery to remove the colon will cure ulcerative colitis and removes the threat of colon cancer. Patients may need an ostomy or an ileal pouch-anal anastomosis, a procedure that connects the small intestine to the anus to help the patient gain more normal bowel function.
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