Medical Health Encyclopedia

Pituitary Cushing’s (Cushing’s disease)

Injury Disease Nutrition Poison Symptoms Surgery Test Special Topic

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Endocrine glands Striae in the popliteal fossa Striae on the leg

Overview Symptoms Treatment Prevention

Pituitary Cushing’s (Cushing’s disease)

Definition:

Pituitary Cushing's is a condition in which the pituitary gland (an organ of the endocrine system) secretes excess adrenocorticotropic hormone (ACTH).

Causes, incidence, and risk factors:

Text Continues Below

---

Cushing's disease is a form of Cushing's syndrome, in which excess cortisol (a stress hormone) is secreted. In the case of Cushing's disease, the problem is caused by a tumor or hyperplasia (excess growth) of the pituitary gland. The pituitary gland is located in the base of the skull and regulates the activities of many glands and body processes.

When ACTH is secreted by the pituitary gland, the adrenal glands release cortisol. In Cushing's disease, there is too much ACTH, which leads to an excess release of cortisol. This hormone, normally released during stressful situations, controls the body's use of carbohydrates, fats, and proteins and also plays a role in suppressing the body's response to inflammation.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.