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Treatment is directed at the underlying cause of hypercalcemia whenever possible. In cases of hyperparathyroidism, surgery may be needed to remove the abnormal parathyroid gland and cure the hypercalcemia.
When hypercalcemia is mild and caused by primary hyperparathyroidism, patients may be followed closely by their physician over time. Severe hypercalcemia causing symptoms and requiring hospitalization is treated aggressively with the following:
- Intravenous fluids
- Bisphosphonates (drugs that stop bone resorption such as pamidronate or etidronate)
- Calcitonin
- Glucocorticoids (steroids, for hypervitaminosis D that is not medication related)
- Hemodialysis (for hypercalcemia that is unresponsive to treatment and is life-threatening)
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