Testicular failure

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Endocrine glands

Male reproductive anatomy

Testicular failure is the inability of the testicles to produce sperm or male hormones.

See also:

• Hypogonadism
• Secondary hypogonadism

Primary hypogonadism - male

Testicular failure is uncommon. Causes include:

• Certain drugs, including glucocorticoids, ketoconazole, and opioids
• Chromosome problems
• Diseases that affect the testicle, including mumps, orchitis, and testicular cancer
• Injury to the testicles
• Testicular torsion

The following things increase the risk for testicular failure:

• Activities that may cause constant, low-level injury to the scrotum, such as riding a motorcycle
• Frequent and heavy use of marijuana
• Undescended testicles at birth

Review Date: 06/22/2009
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Louis S. Liou, MD, PhD, Assistant Professor of Urology, Department of Surgery, Boston University School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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