Familial combined hyperlipidemia

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Coronary artery blockage

Multiple lipoprotein-type hyperlipidemia

Chest pain (angina) may occur. However, there may not be any physical symptoms.

Persons with this condition develop high cholesterol or triglyceride levels during the teenage years. The levels remain high throughout life. They have an increased risk of early coronary artery disease and heart attacks. Those with familial combined hyperlipidemia have a higher rate of obesity and glucose intolerance.

Blood tests will be done to check your levels of cholesterol and triglycerides. Specific tests include:

• LDL test (increased)
• HDL test (decreased)
• Triglycerides test (increased)
• Apolipoprotein B100 test (increased)

Genetic testing is available for one type of familial combined hyperlipidemia.

Review Date: 05/23/2010
Reviewed By: David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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