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Endocrine glands

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Multiple Endocrine Neoplasia (MEN) II

Alternative Names: Sipple's syndrome Treatment: Surgery is needed to remove both the medullary carcinoma of the thyroid and the pheochromocytoma. Medullary carcinoma of the thyroid must be treated with total removal of the thyroid gland and removal of surrounding lymph nodes. Hormone replacement therapy is given after surgery. Text Continues Below Family members should be screened for the RET gene mutation. Expectations (prognosis): Pheochromocytoma is usually benign (not cancer), but the accompanying medullary carcinoma of the thyroid that characterizes this condition is a very aggressive and potentially fatal cancer. Nonetheless, early diagnosis and surgery can often lead to cure. Complications: A complication is the metastasis of cancerous cells. Calling your health care provider: Call your health care provide if you notice symptoms of MEN II.

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