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Polymyositis - adult

Symptoms: Polymyositis is a systemic disease, which means it affects the whole body. Symptoms include:  muscle weakness in the proximal muscles (shoulders, hips, etc.) muscle pain difficulty swallowing shortness of breath hand tremor Patients may also have morning stiffness, joint pain, fatigue, anorexia, weight loss, and fever. Signs and tests: electromyography MRI of affected muscles muscle biopsy serum creatinine, elevated serum aldolase, elevated CPK, elevated References: Text Continues Below Harris ED, Budd RC, Genovese MC, Firestein GS, Sargent JS, Sledge CB. Kelley's Textbook of Rheumatology. 7th ed. St. Louis, Mo: WB Saunders; 2005:1312-1316. Choy E, Hoogendijk J, Lecky B, Winer J. Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD003643. Schnabel A, Hellmich B, Gross WL. Interstitial lung disease in polymyositis and dermatomyositis. Curr Rheumatol Rep. 2005 Apr;7(2):99-105. Rosenkranz H. Polymyositis. eMedicine. March 10, 2005. Available online at: http://www.emedicine.com/emerg/topic474.htm. Accessed October 12, 2005.

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