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Systemic lupus erythematosus Lupus, discoid - view of lesions on the chest Lupus, discoid on a child's face Systemic lupus erythematosus rash on the face Lupus, discoid on the face Antibodies
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Systemic lupus erythematosus
Alternative Names: Disseminated lupus erythematosus; SLE; Lupus; Lupus erythematosus Symptoms: fever fatigue general discomfort, uneasiness or ill feeling (malaise) weight loss skin rash - a "butterfly" rash, aggravated by sunlight sensitivity to sunlight joint pain and swelling arthritis swollen glands muscle aches nausea and vomiting pleuritic chest pain seizures psychosis Additional symptoms that may be associated with this disease: blood in the urine coughing up blood nosebleed swallowing difficulty skin color is patchy red spots on skin fingers that change color upon pressure or in the cold numbness and tingling mouth sores hair loss abdominal pain visual disturbance Signs and tests: Text Continues Below The diagnosis of SLE is based upon the presence of at least four out of eleven typical characteristics of the disease. Tests to determine the presence of these disease manifestations may vary, but will include some of the following: antinuclear antibody (ANA) panel including anti-DNA and anti-Smith antibodies, with the latter two tests generally positive in lupus alone characteristic skin rash or lesions chest x-ray showing pleuritis or pericarditis listening to the chest with a stethoscope to reveal heart friction rub or pleural friction rub urinalysis to show blood, casts, or protein in the urine CBC showing a decrease in some cell types kidney biopsy neurological examination This disease may also alter the results of the following tests: WBC count serum globulin electrophoresis rheumatoid factor urine protein serum protein electrophoresis mononucleosis spot test ESR cryoglobulins Coombs' test - direct complement component 3 (C3) complement antithyroid microsomal antibody antithyroglobulin antibody antimitochondrial antibody anti-smooth muscle antibody Page:  1 | 2 | Next >>