Membranoproliferative GN

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Kidney anatomy

Membranoproliferative GN I; Membranoproliferative GN II; Mesangiocapillary glomerulonephritis; Membranoproliferative glomerulonephritis; Lobular GN; Glomerulonephritis - membranoproliferative; MPGN type I; MPGN type II

Treatment depends on the symptoms. The goals of treatment are to reduce symptoms, prevent complications, and slow the progression of the disorder.

A change in diet may be needed. This may include limiting salt, fluids, or protein to help control high blood pressure, swelling, and the build up of waste products in the blood.

Medicines that may be prescribed include:

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• Blood pressure medications
• Cytotoxic medications
• Dipyridamole with or without aspirin
• Diuretics
• Steroids

Dialysis or kidney transplant may eventually be required to manage kidney failure.

The disorder often slowly gets worse and eventually results in chronic kidney failure. Fifty percent of cases lead to chronic renal failure within 10 years.

• Acute renal failure
• Acute nephritic syndrome
• Nephrotic syndrome
• Chronic renal failure

Call for an appointment with your health care provider if you have symptoms of this condition. Also call for an appointment with your health care provider if symptoms worsen or persist, or if new symptoms develop, including decreased urine output.

Review Date: 08/12/2009
Reviewed By: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, Affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).