Focal segmental glomerulosclerosis

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Male urinary system

Segmental glomerulosclerosis; Focal sclerosis with hyalinosis

Some patients will receive high doses of corticosteroids or a drug called cyclosporine to suppress their immune system.

The goal of treatment is to control the symptoms of nephrotic syndrome and prevent chronic kidney failure.

See also:

• Chronic kidney failure
• Nephrotic syndrome

In general, treatments may include:

• Antibiotics to control infections
• Anti-inflammatory medicines to reduce the immune response
• Dialysis
• Fluid restriction
• Kidney transplant
• Low-fat diet
• Low- or moderate-protein diet (1 gram of protein per kilogram of body weight per day)
• Medicines to treat high blood pressure, high blood cholesterol, and high triglyceride levels
• Salt-reduced diet
• Vitamin D supplements

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See also: Kidney disease - diet

More than half of those with focal or segmental glomerulosclerosis develop chronic kidney failure within 10 years.

• Chronic kidney failure
• End-stage kidney disease
• Infection
• Malnutrition
• Nephrotic syndrome

You should call your doctor if you develop symptoms of this condition, especially if there is fever, pain with urination, or decreased urine output.

Review Date: 06/08/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Herbert Y Lin, MD, PhD, Nephrologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).