Analgesic nephropathy

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Male urinary system

Phenacetin nephritis; Nephropathy - analgesic

There may be no symptoms. Symptoms of chronic kidney disease are often present over time and may include:

• Weakness
• Fatigue
• Increased urinary frequency or urgency
• Blood in the urine
• Flank pain or back pain
• Decreased urine output
• Decreased alertness
  • Drowsiness
  • Confusion , delirium
  • Lethargy
• Decreased sensation , numbness (especially in the legs)
• Nausea , vomiting
• Easy bruising or bleeding
• Swelling , generalized

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A physical examination may show signs of interstitial nephritis or kidney failure.

Blood pressure may be high. The doctor may hear abnormal heart or lung sounds when listening to the chest with a stethoscope. There may be signs of premature skin aging.

Lab tests may show blood and pus in the urine, with or without signs of infection. There may be mild or no loss of protein in the urine.

Tests that may be done include:

• Complete blood count
• Examination of sediment or tissue passed in the urine
• Intravenous pyelogram (IVP)
• Toxicology screen
• Urinalysis

Review Date: 08/13/2009
Reviewed By: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, Affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).