The outcome varies; the syndrome may be acute and short-term or chronic and unresponsive to therapy. The cause and development of complications also affects the outcome.

• Atherosclerosis and related heart diseases
• Renal vein thrombosis
• Acute renal failure
• Chronic renal failure
• Infections, including pneumococcal pneumonia
• Malnutrition
• Fluid overload, congestive heart failure, pulmonary edema

Call your health care provider if symptoms which may indicate nephrotic syndrome occur.

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Call your health care provider if nephrotic syndrome persists or if new symptoms develop, including severe headache, fever, sores on the skin, cough, discomfort with urination, or decreased urine output.

Go to the emergency room or call the local emergency number (such as 911) if convulsions occur.