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Kidney anatomy

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End-stage kidney disease

Alternative Names: Renal failure - end stage; Kidney failure - end stage; ESRD Symptoms: Unintentional weight loss Nausea or vomiting General ill feeling Fatigue Headache Frequent hiccups Generalized itching Greatly decreased urine output No urine output Easy bruising or bleeding May have blood in the vomit or stools Decreased alertness drowsiness, somnolence, lethargy confusion, delirium coma Muscle twitching or cramps Seizures Increased skin pigmentation Skin may appear yellow or brown Nail abnormalities Decreased sensation in the hands, feet, or other areas Signs and tests: The patient usually has a long history of chronic kidney failure, which has progressed. The person may have required dialysis to control chronic renal failure. The urine volume may decrease or urine production may stop totally. Signs of complications commonly are present. Creatinine and BUN levels are chronically high. Creatinine clearance is very low.

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