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Diabetes insipidus - nephrogenic

Alternative Names: Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; Symptoms: Excessive thirst (may be intense or uncontrollable, with a craving for ice water) Excessive urine volume (may exceed 3 to 15 liters per day) Inadequate fluid consumption can result in: Dehydration Dry skin Dry mucous membranes Sunken appearance to eyes Sunken fontanelles (soft spot) in infants Fatigue, lethargy Headache Irritability Low body temperature Muscle pains Rapid heart rate Weight loss Signs and tests: Text Continues Below Examination may indicate dehydration and/or shock if fluid intake is inadequate. The pulse rate may be rapid, with a low blood pressure present. The most significant indication of diabetes insipidus is persistent high urine output regardless of fluid intake. Signs associated with high urine output are: High serum osmolality Low urine osmolality Normal or high ADH levels The kidneys not making a more concentrated urine when the person is given ADH This disease may also alter the results of the following tests: Urine specific gravity Urine concentration test Urine 24h volume Serum sodium

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