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Amyloidosis on the fingers Amyloidosis on the face
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Primary amyloidosis
Alternative Names: Amyloid - primary Symptoms: fatigue numbness of hands and feet weak hand grip weight loss shortness of breath swelling of the extremities swallowing difficulties irregular heart rhythm skin changes enlarged tongue Additional symptoms that may be associated with this disease: weakness urine output, decreased other tongue problems stools, clay colored diarrhea joint pain hoarseness or changing voice Signs and tests: Text Continues Below Your doctor may discover that you have an enlarged liver or spleen. There may be signs of heart failure. If specific organ damage is suspected, testing to confirm amyloidosis of that organ may be performed. For example: biopsy of a tissue or organ will be positive for amyloid. A skin biopsy that includes subcutaneous fat, a rectal mucosa biopsy, or a bone marrow biopsy can help confirm the diagnosis. heart evaluation may reveal arrhythmias, abnormal heart sounds, or signs of heart failure. ECG shows abnormalities. echocardiogram shows poor wall motion because of a stiff heart muscle (cardiomyopathy). kidney function evaluation may reveal renal failure or nephrotic syndrome (excessive protein in the urine). Urinalysis shows protein, casts, or fat bodies. Serum creatinine is increased. BUN is increased. abdominal ultrasound may reveal enlarged liver or spleen. evaluation for carpal tunnel syndrome may reveal involvement of the nerve: nerve conduction velocity shows a conduction block. hand grips are weak because of weakness of the thumb. Page:  1 | 2 | Next >>