Congenital antithrombin III deficiency

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Venous blood clot

Deficiency - antithrombin III - congenital; Antithrombin III deficiency - congenital

Patients will usually have symptoms of a blood clot, including:

• Coughing up blood
• Fainting
• Shortness of breath and pain when taking deep breaths
• Swelling of one leg

A physical examination may show:

• A fast heart rate
• A swollen foot or ankle

The diagnosis is made by checking for low levels of antithrombin III in the patient's blood.

Review Date: 03/02/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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