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The first therapy tried is usually treatment with prednisone. If prednisone does not improve the condition, a splenectomy (removal of the spleen) may be considered.
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Immunosuppressive therapy is given if the person does not respond to prednisone and splenectomy. Imuran and Cytoxan have both been used.
Blood transfusions are given with caution, if indicated for severe anemia, because of the potential that blood may not be compatible and may bring on a reaction.
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