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Tetanus
Alternative Names: Lockjaw Treatment: Control and reverse the tetany with antitoxin (tetanus immune globulin). Give penicillin to kill C. tetani (other antibiotics such as clindamycin, erythromycin, or metronidazole can be used in patients who are allergic to penicillin). Remove and destroy the source of the toxin through surgical exploration and cleaning of the wound (debridement). Treat symptoms. Muscle spasms can be treated with muscle relaxants such as diazepam. Bedrest with a nonstimulating environment (dim light, reduced noise, and stable temperature) may be recommended. Sedation may be necessary to keep the affected person calm. Respiratory support with oxygen, endotracheal tube, and mechanical ventilation may be necessary. Expectations (prognosis): Text Continues Below The death rate is high in children and in the elderly. Wounds on the head or face seem to be more dangerous than those on the body. If the person survives the acute illness, recovery is generally complete. Uncorrected episodes of hypoxia (lack of oxygen) caused by muscle spasms in the throat may lead to irreversible brain damage. Complications: Airway obstruction Respiratory arrest Heart failure Pneumonia Fractures Brain damage due to lack of oxygen during spasms Calling your health care provider: Call your health care provider if you sustain an open wound, particularly if you are injured outdoors or if the wound has otherwise been in contact with soil, and you have not received a tetanus booster (vaccine) within five years or you are not sure of your vaccination status. Page:  1 | 2 | Next >>