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Central nervous system
Central nervous system


Generalized tonic-clonic seizure

Alternative Names:
Seizure - tonic-clonic; Seizure - grand mal; Grand mal seizure; Seizure - generalized

Symptoms:

Many patients have an aura (sensory warning sign) preceding the seizure. This can include a visual, taste, smell, sensory, or other hallucination or dizziness.

The seizure itself involves:
  • loss of consciousness or fainting, usually lasting between 30 seconds and five minutes
  • general muscle contraction and rigidity (tonic posture), usually lasting 15 to 20 seconds
  • violent rhythmic muscle contraction and relaxation (clonic movement), usually lasting for one to two minutes
  • biting the cheek or tongue, clenched teeth or jaw
  • incontinence (loss of urine or stool control)
  • stopped breathing or difficulty breathing during seizure
  • blue skin color
Text Continues Below



Almost all people experience loss of consciousness, and most people experience both tonic and clonic muscle activity.

After the seizure:

  • the person usually begins breathing normally when the seizure is over
  • arousable but sleepy for one hour or longer
  • loss of memory (amnesia) regarding events surrounding the seizure episode
  • headache
  • drowsiness
  • confusion, temporary and mild
  • may be weak for 24-48 hours following seizure (Todd's paralysis)

Signs and tests:

Diagnosis of a grand mal seizure is based on the symptoms and excluding other medical problems that can look like a seizure (such as heart arrythmia). A neuromuscular examination may or may not reveal neurologic deficits (decreases in brain functions) when the person is not actively having seizures.

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