The outlook is largely determined by the underlying cause of the focal seizures. Patients who have recurrent seizures that are not due to a temporary condition (e.g., a drug side effect or infection) have a chronic condition called epilepsy.

Seizures that occur singly or in a closely associated group are commonly triggered by an acute condition such as brain injury and may occur as an isolated incident, or they may develop into a chronic seizure disorder. Seizures within the first 2 weeks of a brain injury do not necessarily mean that a chronic seizure disorder will develop. EEG and MRI findings may help determine whether the condition is likely to become chronic.

Death or permanent brain damage from seizures is rare, but either can occur if the seizure is prolonged or if many seizures occur in close proximity (status epilepticus).

Serious injury can occur if the seizure happens while the person is driving or operating dangerous equipment. These activities may be restricted for people with poorly controlled seizure disorders.

Infrequent seizures, however, need not severely restrict lifestyle. Work, school, and recreation do not necessarily need to be restricted, but precautions should be taken to reduce risks if a seizure should occur.

• progression to generalized seizures
• epilepsy (recurrent seizures)
• prolonged or closely occurring seizures (status epilepticus)
• injury from falls, bumps, biting self
• injury caused by a seizure during driving/operating machinery
• aspiration pneumonia
• permanent brain damage (stroke or other damage)
• side effects of medications (with or without observable symptoms)
• complications of surgery
• women who choose to get pregnant should inform their doctor in advance for appropriate adjustments in medications (many of the anti-epileptic medications can cause birth defects)