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Medical Health Encyclopedia
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Central nervous system
Central nervous system


Syphilitic aseptic meningitis

Alternative Names:
Meningitis - syphilitic

Treatment:

The goals of treatment are to cure the infection and to reduce progression of the disorder. Treatment of the infection reduces new nerve damage and may reduce symptoms, but it does not cure existing damage.

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Penicillin or other antibiotics (such as tetracycline or erythromycin) are given to treat the infection. Treatment may be prolonged to ensure that the infection is completely cleared. Symptoms may improve dramatically after treatment of the infection. A follow-up examination of the cerebrospinal fluid is required to evaluate the effectiveness of antibiotic therapy.

Note: Oral tetracycline is usually not prescribed for children until after all the permanent teeth have erupted. It can permanently discolor teeth that are still forming.

Symptomatic treatment is required for existing neurologic damage. Emergency treatment of seizures may be required! Anticonvulsants such as phenytoin may be needed to control seizures.

Assistance or supervision may be needed if the person is unable to function in self-care activities (eating, dressing, etc.). Confusion and other mental changes may improve or be prolonged after antibiotic treatment.



Expectations (prognosis):

A progressive disability is possible. Early death is common, with death caused directly by the neurologic damage (resulting in decreased function of body systems) or by cardiovascular damage that also occurs with late syphilis infections.

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