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Medical Health Encyclopedia
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Central nervous system
Central nervous system


Multiple system atrophy

Alternative Names:
Shy-Drager syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome
Text Continues Below



Symptoms:
  • Dizziness or fainting when arising or after standing still
  • Impotence
  • Loss of sweating of any part of the body
  • Loss of control of bowels or bladder
  • Vision changes, decreased or blurred vision
  • Muscle rigidity
    • Stiffness
    • Difficulty bending arms or legs
  • Posture difficulties: may be unstable, stooped, or slumped over
  • Movement difficulties
  • Slow movements
    • Difficulty beginning to walk or initiating any voluntary movement
    • Small steps followed by the need to run to maintain balance
    • Freezing of movement when the movement is stopped, unable to resume movement
  • Muscle aches and pains (myalgia)
  • Tremors: may be present in varying degrees or may not be present
    • May occur at rest or at any time
    • May become severe enough to interfere with activities
    • May be worse when tired, excited, or stressed
    • Finger-thumb rubbing (pill rolling tremor): may be present
    • May occur with any action such as holding a cup or other eating utensils
  • Changes in facial expression
    • Reduced ability to show facial expressions
    • "Mask" appearance to face
    • Staring
    • May be unable to close mouth
  • Voice and/or speech changes
  • Difficulty chewing or swallowing (occasionally)
  • Loss of fine motor skills
    • Difficulty writing: may be small and illegible
    • Difficulty eating
    • Difficulty with any activity that requires small movements
  • Frequent falls
  • Mild decline in intellectual function (may occur)
Additional symptoms that may be associated with this disease:

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