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Central nervous system
Overview
Symptoms
Treatment
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Multiple system atrophy
Alternative Names:
Shy-Drager syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome
Text Continues Below
Symptoms:
Dizziness
or
fainting
when arising or after standing still
Impotence
Loss of sweating of any part of the body
Loss of control of bowels or bladder
Vision changes, decreased or
blurred vision
Muscle rigidity
Stiffness
Difficulty bending arms or legs
Posture difficulties: may be unstable, stooped, or slumped over
Movement difficulties
Loss of balance
Gait (walking pattern) changes
Shuffling
Slow movements
Difficulty beginning to walk or initiating any voluntary movement
Small steps followed by the need to run to maintain balance
Freezing of movement when the movement is stopped, unable to resume movement
Muscle aches
and pains (myalgia)
Tremors
: may be present in varying degrees or may not be present
May occur at rest or at any time
May become severe enough to interfere with activities
May be worse when tired, excited, or stressed
Finger-thumb rubbing (pill rolling tremor): may be present
May occur with any action such as holding a cup or other eating utensils
Changes in facial expression
Reduced ability to show facial expressions
"Mask" appearance to face
Staring
May be unable to close mouth
Voice and/or speech changes
Slow speaking
Voice is low-volume
Monotone
Difficulty speaking
Difficulty chewing
or swallowing (occasionally)
Loss of fine motor skills
Difficulty writing: may be small and illegible
Difficulty eating
Difficulty with any activity that requires small movements
Frequent falls
Mild decline in intellectual function (may occur)
Additional symptoms that may be associated with this disease:
Depression
Confusion
Dementia
Seborrheic dermatitis
Sleep-related breathing difficulties, especially sleep apnea and air passage obstruction accompanied by a harsh vibrating sound
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