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The goal of treatment is to reduce inflammation. Treatment usually does not require hospitalization unless tongue swelling is severe.
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Good oral hygiene is necessary, including thorough tooth brushing at least twice a day, and flossing at least daily.
Corticosteroids such as prednisone may be given to reduce the inflammation of glossitis. For mild cases, topical applications (such as a prednisone mouth rinse that is not swallowed) may be recommended to avoid the side effects of swallowed or injected corticosteroids.
Antibiotics, antifungal medications, or other antimicrobials may be prescribed if the cause of glossitis is an infection. Anemia and nutritional deficiencies must be treated, often by dietary changes or other supplements. Avoid irritants (such as hot or spicy foods, alcohol, and tobacco) to minimize the discomfort.
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