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If the diagnosis of compartment syndrome is made promptly and surgical release performed, the outlook is excellent for recovery of the muscles and nerves inside the compartment. However, the overall prognosis will be determined by the injury leading to the syndrome.
If there is a delay in diagnosis, there can be permanent nerve injury and loss of muscle function. This is more common when injured person is unconscious or heavily sedated and incapable of complaining. Permanent nerve injury can occur after 12-24 hours of compression.
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