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Hallervorden-Spatz disease
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| Hallervorden-Spatz disease |
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Definition:
Hallervorden-Spatz disease is an inherited, degenerative disease that usually begins in childhood and involves progressive muscle rigidity, weakness, and movement disorder. Causes, incidence, and risk factors:
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Most cases of Hallervorde-Spatz are due to a mutation in the gene responsible for making a protein called pantothenate kinase 2. Patients with a mutated form of this gene accumulate iron in parts of the brain, especially the basal ganglia.
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