Leukemia

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Acute lymphocytic leukemia - photomicrograph	Antibodies	Auer rods	Bone marrow aspiration
Chronic lymphocytic leukemia - microscopic view	Chronic myelocytic leukemia	Chronic myelocytic leukemia	Chronic myelocytic leukemia - microscopic view
Cryoglobulinemia - of the fingers

Leukemia is a group of cancers that begins in the blood forming cells of the bone marrow.

The term "leukemia" literally means "white blood." White blood cells (leukocytes) are used by the body to fight off infections and other foreign substances. They are made in the bone marrow.

Leukemia leads to an uncontrolled increase in the number of immature white blood cells (or blasts).

Over time, these cancerous blast cells fill up the bone marrow and prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made. Life-threatening symptoms may then develop.

The blast cells spill out of the marrow into the bloodstream and lymph system. They can also travel to the brain and spinal cord (the central nervous system) and other parts of the body.

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Leukemias are divided into two major types:

• Acute (which progresses quickly with many immature white cells)
• Chronic (which progresses more slowly and has more mature white cells)

For information about a specific type of leukemia, see the following:

• Acute lymphocytic leukemia (ALL)
• Acute myelogenous leukemia (AML)
• Chronic lymphocytic leukemia (CLL)
• Chronic myelogenous leukemia (CML)
• Hairy cell leukemia

For information about leukemia support groups, see: Leukemia resources

Review Date: 03/02/2009
Reviewed By: David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).