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Agammaglobulinemia

Alternative Names: Bruton's agammaglobulinemia; X-linked agammaglobulinemia Treatment: The goal of treatment is to reduce the number and severity of infections as well as provide genetic counseling to affected families. Text Continues Below Intramuscular or intravenous injections of immune serum globulin (gamma globulin, IVIg) help to boost the immune system. Infusions of blood plasma into a vein gives a quick supplement to the immune system (plasma contains antibodies, including IgG, IgM, and IgA). High doses of high titer gamma globulin are needed for severe infections. Antibiotics are frequently necessary for the treatment of bacterial infections. Expectations (prognosis): Treatment with immune globulins has improved the health of people with agammaglobulinemia. Without treatment, most severe infections are fatal. Complications: autoimmune disorders eczema malabsorption syndromes arthritis chronic sinus or pulmonary disease Calling your health care provider: Call for an appointment with your health care provider if you or your child has experienced frequent infections. Call for an appointment with your health care provider if you have a family history of agammaglobulinemia or other immunodeficiency disorder and you are planning to have children -- ask the provider about genetic counseling.

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