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Medical Health Encyclopedia
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Antibodies
Antibodies


Graft-versus-host disease

Alternative Names:
GVHD

Treatment:

Treatment consists of suppressing the immune response, but doing so without damaging the new marrow. Immune suppressants often used to treat cancer are also carefully used in decreased dosages to suppress or prevent graft-versus-host disease.

Text Continues Below



Treatment of acute GVHD includes:

  • High-dose corticosteroids
  • Antibodies to T cells are a second-line option


Expectations (prognosis):

The outcome varies. Sometimes treatment of the condition can lead to severe complications.



Complications:
  • Moderate-to-severe damage to the liver, lung, or gastrointestinal tract
  • Severe infection


Calling your health care provider:

As a rule, people with bone marrow grafts are very closely monitored. However, if any of the above symptoms appear, call your health care provider immediately.




A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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