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Congenital afibrinogenemia

Treatment: Patients may be transfused with plasma (the liquid portion of the blood) or cryoprecipitate (a blood product containing concentrated fibrinogen) to treat bleeding episodes or in preparation for surgery needed to treat other conditions. People with this condition should be immunized with the hepatitis B vaccine because of the increased risk of developing hepatitis due to transfusion. Expectations (prognosis): Significant bleeding is common with this condition and these episodes may be severe, even fatal. Bleeding in the brain is a leading cause of death in patients with this disorder. Complications: Bleeding from the umbilical cord Bleeding from the mucous membranes Gastrointestinal bleeding Intracranial bleeding Clotting with treatment Development of antibodies (inhibitors) to fibrinogen with treatment Calling your health care provider: Text Continues Below Call your health care provider or seek emergency care if excessive bleeding occurs. Notify your surgeon before you have surgery if you know or suspect you have a blood disorder.

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