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The oral or genital lesions usually heal on their own in 7 to 10 days unless an individual has an underlying condition that weakens the immune system, in which case the infection may be more severe and last longer.
Once infected, the virus spreads to nerve cells and stays in the body for the rest of a person's life . It may intermittently reactivate and cause symptoms, or flares. Recurrences may be precipitated by overexposure to sunlight, fever, stress, acute illness, and medications or conditions that weaken the immune system (such as cancer, HIV/AIDS, or use of corticosteroids).
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