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Antibodies

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Hereditary angioedema

Symptoms: Swelling in the arms, legs, lips, eyes, tongue, or throat Airway obstruction -- throat swelling and sudden hoarseness Repeat episodes of abdominal cramping without obvious cause Intestinal swelling can be severe and include vomiting, dehydration, pain, and occasionally shock Patients may have several hours' warning before swelling becomes severe. Signs and tests: Decreased C1 inhibiting factor activity Decreased C4 and C2 levels, part of the complement test

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