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Gestational trophoblastic disease
Alternative Names: Chorioblastoma; Choriocarcinoma; Trophoblastic tumor; Chorioepithelioma; Invasive/malignant mole; Gestational trophoblastic neoplasia Treatment: After an initial diagnosis, a careful history and examination are done to rule out metastasis (spread to other organs). Chemotherapy is the treatment of choice. Text Continues Below A hysterectomy is rarely required, due to choriocarcinoma's extreme sensitivity to chemotherapy. More than 90% of women with malignant, nonmetastatic disease are able to maintain reproductive capabilities. Support Groups: For additional information, see cancer resources. Expectations (prognosis): Nearly all women with malignant, nonmetastatic disease are cured, with more than 90% preserving reproductive function. Some women with malignant, metastatic disease may have a poor prognosis if they meet one of the following conditions: Disease has spread to the liver or brain. Serum HCG measurement is greater than 40,000 mIU/ml at the time treatment is started. Having received prior chemotherapy. Having symptoms (or the preceding pregnancy) for more than 4 months before treatment. Term pregnancy is associated with diagnosis. About 66% of women having a poor prognosis experience remission (a disease-free state). Almost all women who receive a good prognosis with malignant, metastatic disease that does not meet one of these conditions experience remission. Complications: Page:  1 | 2 | Next >>