Prader-Willi syndrome

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Obesity represents the greatest problem to health. Limiting caloric intake will control the obesity but the family, neighbors, school, and other institutions must cooperate closely as the child will attempt to obtain food wherever possible. Exercise can increase lean body mass in children with Prader-Willi syndrome.

Growth hormone has also been shown to improve physical strength and agility in patients with Prader-Willi syndrome. There have been some concerns regarding the effect of GH on lung function in children with this condition. Parents should discuss the possible side effects with the child's doctor.

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A very small penis in the male infant may be corrected with testosterone.

Low levels of sex hormones may be corrected at puberty with hormone replacement.

For additional resources and support, see:

• Prader-Willi Alliance -- www.prader-willi.org
• Prader-Willi Syndrome Association --www.pwsausa.org

Appropriate education will be needed for the affected person's IQ level. Weight control will allow for a much more comfortable and healthful life.

• Diabetes
• Right-sided heart failure
• Orthopedic problems

Call your health care provider if your child has symptoms of this condition. The disorder is frequently suspected at birth.

Review Date: 11/02/2009
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).