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Diphtheria antitoxin is given as an intramuscular or intravenous injection as soon as the diagnosis is suspected. The infection is then treated with antibiotics, such as penicillin or erythromycin.
People with diphtheria may require hospitalization for supportive treatment and during the administration of antitoxin. Insertion of an endotracheal tube and/or removal of the obstructing membrane may be required if airway obstruction is present. Intravenous fluids, oxygen, bed rest, and cardiac monitoring (due to the possibility of myocarditis) are usually indicated.
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Immunization or booster shots for all contacts of the infected person, including health care personnel, should be given. Individuals found to be carriers of diphtheria are treated with antibiotics as well.
Protective immunity lasts only 10 years from the time of vaccination, so it is important for adults to get a booster of tetanus-diptheria (Td) vaccine every 10 years.
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