Aminophylline overdose

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Theophylline overdose; Xanthine overdose

The major life-threatening events of theophylline intoxication are seizures and heart rhythm disturbances.

Symptoms in adults may include:

• Gastrointestinal
  • Increased appetite
  • Increased thirst
  • Nausea
  • Vomiting (possibly with blood)
• Heart and blood
  • High or low blood pressure
  • Irregular heartbeat
  • Rapid heart rate
  • Pounding heartbeat (palpitations)
• Lungs
  • Breathing difficulty
• Muscles and joints
  • Muscle twitching and cramping
• Nervous system
  • Confusion
  • Convulsions
  • Dizziness
  • Fever
  • Hallucinations (thinking something is there, but it's not)
  • Headache
  • Irritability
  • Psychosis
  • Restlessness
  • Sweating
  • Trouble sleeping

Symptoms in babies may include:

• Gastrointestinal
  • Nausea
  • Vomiting
• Heart and blood
  • Irregular heartbeat
  • Low blood pressure
  • Rapid heartbeat
  • Shock
• Lungs
  • Rapid, deep breathing
• Muscles and joints
  • Muscle cramps
  • Twitching
• Nervous system
  • Convulsions
  • Irritability
  • Tremors

Review Date: 02/03/2009
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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