Hemolytic crisis

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Hemolysis - acute

If you have any of the following symptoms, contact your doctor:

• A decrease in the amount of urine you produce
• Fatigue, pale skin, or other symptoms of anemia, especially if these symptoms get worse
• Urine that looks red, red-brown, or brown (tea-colored)

Emergency treatment may be necessary. This may include a hospital stay, oxygen, blood transfusions, and other treatments.

When your condition is stable, your doctor will perform a physical examination and ask questions, such as:

• When did you first notice symptoms?
• What symptoms did you notice?
• Do you have a history of hemolytic anemia, G6PD deficiency, or a kidney disorder?
• Does anyone in your family have a history of hemolytic anemia or abnormal hemoglobin proteins?

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The physical examination may occasionally show swelling of the spleen (splenomegaly).

Tests may include:

• Blood chemistry panel
• Complete blood count (CBC)
• Coombs' test
• Kidney or abdominal CT scan
• Kidney or abdominal ultrasound
• Serum free hemoglobin
• Urine free hemoglobin

Review Date: 01/31/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).