Nikolsky’s sign

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Nikolsky's sign

Skin layers

Call your health care provider if you or your child develop painful loosening, redness, and blistering of the skin without an obvious cause.

The conditions associated with Nikolsky's sign are serious, and most people are sent to the hospital. You will be asked for your medical history and given a physical examination. You may be given fluid and antibiotics through a vein (intravenously).

Your doctor may ask the following questions:

• When did you first notice that the skin was red or blistered?
• What other symptoms occur at the same time?

Review Date: 03/11/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Roy Colven, MD, Dermatologist, Associate Professor of Medicine, University of Washington Medical School, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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