|
There are many antigens besides the major ones (A, B, and Rh). Many minor antigens are not routinely detected during blood typing. If allowed to go unrecognized, they can initiate a blood transfusion reaction, usually of less magnitude than that of a major blood group incompatibility.
Text Continues Below

These minor antigens can be detected by cross-matching, which consists of incubating the recipient's serum with the donor's red blood cells (RBCs) in a saline solution followed by the addition of Coombs serum (see Coombs' test - indirect).
|