Serum TBG level

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Serum thyroxine binding globulin; TBG level

If electrophoresis is used, normal values may range from 10 mg/100 mL - 24 mg/100 mL.

If radioimmunoassay is used, then a normal range is 1.3 - 2.0 mg/100 mL.

Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

Increased TBG levels may be due to:

• Acute intermittent porphyria
• Hypothyroidism
• Liver disease
• Pregnancy (TBG levels are normally increased during pregnancy.)

Note: TBG levels are normally high in newborns.

Decreased TBG levels may be due to:

• Acute illness
• Acromegaly
• Hyperthyroidism
• Malnutrition
• Nephrotic syndrome
• Stress from surgery

Review Date: 05/10/2010
Reviewed By: Frank A. Greco, MD, PhD, Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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