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Growth hormone stimulation test


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Growth hormone stimulation test
Growth hormone stimulation test
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Definition

The growth hormone (GH) stimulation test measures the level of growth hormone (GH) in the blood after you receive medication that triggers the release of GH, such as arginine or GH-releasing hormone. The test measures the ability of the pituitary gland to release GH.

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Alternative Names

Arginine test; Arginine-GHRH test


How the test is performed

The site is cleaned with germ-killing medicine (antiseptic). An IV is usually placed in a vein, typically in the inside of the elbow or the back of the hand.

The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.




Next, the health care provider gently inserts a needle into the vein. The needle is removed while the IV is left in the vein. The elastic band is removed from your arm.

Your blood will be drawn five times. To prevent many punctures of the vein, samples will be taken through the IV line instead of re-inserting the needle each time.

The first sample will be drawn between 6 a.m. and 8 a.m. Then you will receive arginine through a vein for 30 minutes. After the 30-minute infusion, GH-releasing hormone is given to you through a vein. Then four more blood samples are drawn, once every 30 minutes.

Sometimes arginine or GH-releasing hormone is given alone for this test. Which form of the test is used depends on your health care provider's preferences.

Let your doctor know if you have severe kidney or liver disease, because an infusion of arginine could be risky for you.


How to prepare for the test

Do not eat and limit physical activity for 10 - 12 hours before the test to avoid changing the results.

Your health care provider may ask that you stop taking certain medications before the test, as some medications can affect results. (Do not stop taking any medications without first talking to your health care provider.)

You will be asked to relax for at least 90 minutes before the test, because exercise or increased activity can change GH levels.

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