Neonatal cystic fibrosis screening

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Infant blood sample

Cystic fibrosis screening - neonatal; Immunoreactive trypsinogen; IRT test

Risks associated with the test include:

• Infection (a slight risk any time the skin is broken)
• Anxiety over false positive tests
• False reassurance over false negative tests

The test results do not reveal the severity of the CF. False-positives may occur.

Other tests that look for genetic changes known to cause cystic fibrosis may also be used to screen for CF.

Review Date: 06/01/2011
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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