LDH isoenzymes

A
• B
• C
• D
• E
• F
• G
• H
• I
• J
• K
• L
• M
• N
• O
• P
• Q
• R
• S
• T
• U
• V
• W
• X

LD; Lactic (lactate) dehydrogenase isoenzymes

Because LDH can be found in many tissues in the body, total LDH is not specific for heart disease.

Normally, the level of LDH-2 is greater than LDH-1. However, after a heart attack, LDH-1 is generally higher than LDH-2. This is called a "flipped" LDH pattern.

The LDH level rises within 24 - 72 hours after a heart attack, peaks in 3 - 4 days, and returns to normal in about 14 days.

Greater-than-normal LDH levels may suggest:

• Heart attack
• Hemolytic anemia
• Hypotension
• Infectious mononucleosis
• Intestinal ischemia (blood deficiency) and infarction (tissue death)
• Liver disease such as hepatitis
• Muscle injury
• Muscular dystrophy
• Pancreatitis
• Lung tissue death
• Stroke
• Ischemic cardiomyopathy

Review Date: 02/01/2011
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

---

---