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Blood test

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CPK isoenzymes

Alternative Names: Creatine phosphokinase - isoenzymes; Creatine kinase - isoenzymes; CK - isoenzymes What abnormal results mean: Higher-than-normal CPK-1 levels may occur with the following: Brain cancer Brain injury (due to trauma, stroke, or bleeding in the brain) Electroconvulsive therapy Pulmonary infarction Seizure Higher-than-normal CPK-2 levels may occur with the following: Heart attack There is a significant rise in CPK-2 levels in the first 2 - 3 hours after a heart attack. This test is used to diagnose a heart attack. Text Continues Below The extent of the elevation depends on the severity of the heart attack. CPK levels may remain elevated up to 24 hours after a heart attack, and sometimes even longer. Myocarditis (inflammation of the heart muscle usually due to a virus) Electrical injuries Trauma to the heart (for instance, from a car accident) Heart defibrillation (purposeful shocking of the heart by medical personnel) Open heart surgery Higher-than-normal CPK-3 levels may occur with the following: Crush injuries of skeletal muscle Multiple intramuscular injections Muscular dystrophy Myositis (skeletal muscle inflammation) Post-electromyography (a test of nerve and muscle function) Recent seizures Recent surgery Rhabdomyolysis (skeletal muscle damage due to drugs or prolonged immobilization) Strenuous exercise

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