Immunoelectrophoresis - serum

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IEP - serum; Immunoglobulin electrophoresis - serum; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis

No monoclonal antibodies are detected.

Abnormal results may be due to certain types of cancer such as multiple myeloma or chronic lymphocytic leukemia.

Cells related to these types of cancer produce a type of protein called a monoclonal immunoglobulin, which can be detected with this test. However, some people have monoclonal immunoglobulins, but do not have cancer. This is called “monoclonal gammopathy of unknown significance," or MGUS.

Review Date: 06/02/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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