ACE levels

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Serum angiotensin-converting enzyme; SACE

Normal values vary based on your age and the test method used. Typically, adults have ACE levels less than 40 micrograms/L.

Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

Increased ACE levels may be a sign of sarcoidosis. However, increased ACE levels may also be seen in several other disorders, including:

• Active histoplasmosis
• Amyloidosis
• Asbestosis
• Berylliosis
• Diabetes
• Emphysema
• Gaucher's disease
• Hepatitis
• Hodgkin's disease
• Hyperthyroidism
• Idiopathic pulmonary fibrosis
• Leprosy
• Lung cancer
• Nephrotic syndrome
• Primary biliary cirrhosis
• Pulmonary embolism
• Scleroderma
• Silicosis
• Tuberculosis

A decrease in ACE levels may indicate:

• Steroid therapy (usually prednisone)
• Therapy for sarcoidosis

Review Date: 11/15/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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