Osmolality - urine

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Female urinary tract

Male urinary tract

Osmolality test

Normal values are as follows:

• Random specimen: 50 to 1400 milliosmoles per kilogram (mOsm/kg)
• 12 to 14 hour fluid restriction: Greater than 850 mOsm/kg

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

Abnormal results are indicated as follows:

Greater-than-normal measurements may indicate:

• Addison's disease (rare)
• Congestive heart failure
• Dehydration
• Glycosuria
• Renal artery stenosis
• Shock
• Syndrome of inappropriate ADH secretion

Lower-than-normal measurements may indicate:

• Aldosteronism (very rare)
• Diabetes insipidus (rare)
• Excess fluid intake
• Kidney failure
• Renal tubular necrosis
• Severe pyelonephritis

Additional conditions under which the test may be performed:

• Complicated UTI (pyelonephritis)
• High blood sodium level
• Low blood sodium level
• Excessive urination

Review Date: 08/07/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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