Creatinine clearance

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Creatinine tests

Clearance is often measured as milliliters/minute (ml/min). Normal values are:

• Male: 97 to 137 ml/min.
• Female: 88 to 128 ml/min.

Note: Normal values ranges may vary slightly among different laboratories.

Abnormal results (lower-than-normal creatinine clearance) may indicate:

• Acute tubular necrosis
• Bladder outlet obstruction
• Congestive heart failure
• Dehydration
• Glomerulonephritis
• Renal ischemia (blood deficiency
• Renal outflow obstruction (usually must affect both kidneys to reduce the creatinine clearance)
• Shock
• Acute renal failure
• Chronic renal failure
• End-stage renal disease

Review Date: 08/10/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).

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