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Fibrinogen

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Why the test is performed:

This test may be performed when abnormal blood clotting is present, particularly if there is excessive bleeding.

Text Continues Below



Fibrinogen is a protein produced by the liver. Fibrinogen helps stop bleeding by helping blood clots to form. During normal blood clotting:

  • Fibrinogen is broken down by an enzyme called thrombin into short fragments of fibrin. Thrombin also activates a substance called Factor XIII.
  • Factor XIII helps weave the fibrin fragments into a complex lattice, closing off injured blood-vessel walls.
  • Blood platelets attach to the fibrin fragments, clumping together to form blood clots and stop bleeding.


The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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