Prothrombin time (PT)

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Prothrombin time (PT) is a blood test that measures the time it takes for the liquid portion (plasma) of your blood to clot.

See also: Partial thromboplastin time (PTT)

PT; Pro-time; Anticoagulant-prothrombin time

The health care provider uses a needle to take blood from one of your veins. The blood collects into an airtight container. You may be given a bandage to stop any bleeding. If you are taking a medicine called heparin, you will be watched for signs of bleeding.

The laboratory specialist will add chemicals to the blood sample and see how long it takes for the plasma to clot.

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Make sure your doctor knows about all the medicines you are taking, including over-the-counter medicines, herbs, and supplements. Your doctor may tell you to stop taking certain drugs before the test. For example, blood thinners can affect the results of this test.

Do not stop taking any medicine without first talking to your doctor.

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Your doctor may order this test if you have signs of a blood clotting disorder.

If you are taking a blood thinning medicine called warfarin, your health care provider will check your PT or prothrombin time regularly.

When you bleed, the body launches a series of activities that help the blood clot. This is called the coagulation cascade. The PT test looks at special proteins (called coagulation factors) that are involved in this event, and measures their ability to help blood clot.

Review Date: 02/13/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).